PDGF

PDGF (Platelet-Derived Growth Factor) is used in aesthetic treatments that promote natural skin rejuvenation, boost collagen production, and support tissue repair. At Hi, Finch, we use PDGF to enhance results from microneedling and under eye treatments, helping to reduce fine lines, improve skin texture, accelerate post-procedure healing, and improve under eye wrinkles and dark circles. This anti-aging serum is perfect for patients seeking smoother, firmer, and more radiant skin through natural, regenerative methods.

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Onset

Results seen after 2 weeks with continued improvements for several weeks

Frequency

3 monthly sessions, then annually for injection maintenance. 3 monthly sessions then maintenance for skin health

Pricing

PDGF Injections - $900/area
Add-on to microneedling - $450

Suitable for:

  • Collagen stimulation
  • Fine lines and wrinkles
  • Improvement of skin texture
  • Acne scarring
  • Skin regeneration
  • Skin dullness
  • Skin laxity
  • Anti-aging
  • Under eye hollows / dark under eye circles
  • Add-on to microneedling treatment for accelerated healing and enhanced results

What to expect

  • Schedule your treatment at least 2 weeks before major events since you may experience redness and swelling after the procedure.
  • Increase hydration for 1 week prior to your appointment.
  • Inform the cosmetic provider of all your ongoing medications and medical history.
  • Avoid Accutane for at least 6 months before the treatment.
  • Temporarily discontinue blood-thinning medications for a week before the treatment. Temporarily discontinue topical retinoids for 24 hours before the treatment. It is recommended to discontinue the use of Aspirin, NSAIDS, Ginkgo Biloba, Garlic, Ginseng, St. John’s Wort, Flax Oil, Cod Liver Oil, Vitamin A, Vitamin E or any other essential fatty acids at least 3 days to 1 week before and after treatment to minimize bruising or bleeding. Please consult with your primary physician prior to discontinuing any medications.
  • Postpone your PRF if you have a skin rash on the treatment site.
  • Your provider will examine your skin and discuss your goals.
  • Your skin will be cleansed, and a numbing cream may be applied to ensure comfort.
  • A small sample of your blood will be drawn..
  • The blood sample will be spun in a centrifuge to isolate the platelet-rich-fibrin.
  • The ezPRF sample will be injected or microneedled into the targeted areas on your skin to boost collagen production.
  • The remaining EZPRF sample may be massaged into your skin after microneedling treatment.
  • You may experience mild redness, swelling, and sensitivity for a few days.
  • You can resume your daily activities immediately.
  • Your skin may feel dry 3 days after microneedling.
  • Avoid strenuous workouts for 24 hours.
  • Avoid direct sunlight, self-tanners, and tanning beds.
  • Use broad-spectrum SPF 30+ sunscreen when you go outside.

Frequently Asked Questions

What is PDGF?

PDGF stands for Platelet-Derived Growth Factor, a natural protein found in your blood that plays a key role in healing and skin regeneration. PDGF+ by Ariessence is an exact copy of the human derived growth factor found in our blood. Because PDGF is made in a lab, the product is highly purified and concentrated. PDGF can be 1,000 to 300,000 more concentrated than your own blood, because the concentration of growth factors and platelets found in PRF can vary due to many factors including hydration and health status of the patient.

What is the difference between PRF and PDGF?

PRF (Platelet-Rich Fibrin) is a natural product made from your own blood. It contains a concentrated mix of platelets, white blood cells, and fibrin that work together to stimulate healing, regenerate tissue, and boost collagen production. PRF EZgel is typically used for under-eye rejuvenation, hair restoration, and facial volume enhancement, and is injected directly into the skin. PRF liquid is typically used topically to enhance the effects of microneedling.

PDGF (Platelet-Derived Growth Factor) is just one of the key components naturally found in PRF. It can also be used on its own in the form of a topical growth factor serum. PDGF is applied after procedures like microneedling or PRF injections to enhance healing, reduce inflammation, and further support collagen production and skin repair. Off-label uses of PDGF include injections around the eye for volume loss, tissue and skin repair, fine lines, and dark circles.

In short, PRF is the full, natural concentrate, while PDGF is a purified, targeted ingredient that boosts the effects of skin treatments and speeds up recovery.