PRF (Platelet-Rich Fibrin) is a natural product made from your own blood. It contains a concentrated mix of platelets, white blood cells, and fibrin that work together to stimulate healing, regenerate tissue, and boost collagen production. PRF EZgel is typically used for under-eye rejuvenation, hair restoration, and facial volume enhancement, and is injected directly into the skin. PRF liquid is typically used topically to enhance the effects of microneedling.
PDGF (Platelet-Derived Growth Factor) is just one of the key components naturally found in PRF. It can also be used on its own in the form of a topical growth factor serum. PDGF is applied after procedures like microneedling or PRF injections to enhance healing, reduce inflammation, and further support collagen production and skin repair. Off-label uses of PDGF include injections around the eye for volume loss, tissue and skin repair, fine lines, and dark circles.
In short, PRF is the full, natural concentrate, while PDGF is a purified, targeted ingredient that boosts the effects of skin treatments and speeds up recovery.