
Pure PDGF: How This Natural Growth Factor Helps Heal Skin and Boost Microneedling Results
Kasey BennettAs a nurse practitioner, I’m always looking for treatments and ingredients that help the body heal and renew itself naturally. One of the most exciting and well-studied ingredients we now use in skin rejuvenation is pure PDGF — short for Platelet-Derived Growth Factor.
Whether you’re trying to smooth fine lines, improve skin texture, or enhance collagen production, PDGF is a powerful tool that can help. Today, I want to explain what PDGF is, how it’s been used in medicine for years, and how it’s now transforming skin treatments like microneedling.
What Is Pure PDGF?
PDGF is a natural protein your body produces to help repair and rebuild tissue. When you have an injury, like a cut or scrape, PDGF is released to signal the body to start healing. It encourages new cell growth, blood vessel formation, and collagen production — all the things your skin needs to recover and look healthy.
How Has PDGF Been Used in Medicine?
Before it became popular in skincare and aesthetics, pure PDGF was widely used in medical settings for its ability to accelerate healing. In fact, one of its most common applications has been in treating chronic wounds, like diabetic foot ulcers and other slow-healing wounds. Doctors found that applying PDGF to these wounds helped stimulate tissue repair, speed healing, and improve outcomes for patients who previously struggled to heal on their own.
This medical history shows just how powerful PDGF can be when it comes to repairing and regenerating tissue — which is exactly why we now use it in advanced skin treatments.
How Does Pure PDGF Help in Aesthetic Treatments?
In aesthetics, we use pure PDGF for its ability to:
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Stimulate collagen production to help firm and plump the skin
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Encourage skin cell turnover for smoother texture and more even skin tone
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Support tissue repair after treatments that create controlled injury to the skin, like microneedling
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Minimize the appearance of scars and reduce fine lines over time
Microneedling with Pure PDGF: Why It Works So Well
Microneedling is a treatment that uses tiny needles to create micro-injuries in the skin. This process triggers your body’s natural healing response and stimulates collagen production. When we apply pure PDGF during a microneedling session, we enhance this process dramatically.
The microchannels created by microneedling allow the PDGF to absorb directly into the skin, where it immediately gets to work supporting collagen growth and speeding up tissue repair. This combination helps improve skin texture, reduce fine lines, fade scars, and create an overall firmer, more youthful appearance.
Is Microneedling with PDGF Right for You?
If you’re looking to smooth fine lines, improve skin texture, fade acne scars, and boost collagen production naturally, microneedling with PDGF could be an excellent option.
Final Thoughts
Pure PDGF has a long track record of helping the body heal, both in medicine and aesthetics. When paired with microneedling, it helps your skin rebuild stronger and smoother from the inside out. If you’re curious about how this treatment can work for you, schedule a consultation — I’d love to help you achieve healthy, radiant skin!
Role of platelet-derived growth factors in physiology and medicine